Sunday , August 18 2019


Scientists Reveal Amino Acids Supply Most Building Blocks for Tumor Cells

New research shows that amino acids, not glucose, account for the majority of cell mass in proliferating mammalian cells. Cancer cells are notorious for their ability to divide uncontrollably and generate hordes of new tumor cells. Most of the fuel consumed by these rapidly proliferating cells is glucose, a type of sugar. Scientists had believed that most of the cell ... Read More »

MIT Research Shows How Diet Influences Colon Cancer

“Not only does the high-fat diet change the biology of stem cells, it also changes the biology of non-stem-cell populations, which collectively leads to an increase in tumor formation,†Omer Yilmaz says. New research from MIT reveals ties high-fat diet to changes in intestinal stem cells, helping to explain an increased cancer risk. Over the past decade, studies have found ... Read More »

New Yale Study Pinpoints Key Protein in Severe Vascular Disease

Fate mapping indicates that pre–existing smooth muscle cells contribute to the excess aortic smooth muscle in elastin mutants. New research from Yale University investigates factors that squeeze, or narrow, the aorta in a common vascular disease, revealing a target for potential new treatments. Individuals who suffer from supravalvular aortic stenosis, a condition characterized by narrowing of the aorta, have only ... Read More »

New Study Shows Even Moderate Alcohol Consumption Can Harm People with HIV

A newly published study from Yale University shows that moderate alcohol consumption is more harmful to people with HIV than uninfected individuals, raising the risk of both mortality and other negative health effects. The Yale study is the first to demonstrate the increased harm among patients who have suppressed HIV with modern antiretroviral treatment (ART). Research has shown that it ... Read More »

Biochemists Identify Another Piece of the Parkinson’s Disease Pathology Puzzle

Parkinson’s researchers used proteomics to identify Rab proteins as a physiological substrate of LRRK2, a Parkinson’s drug target. This finding may accelerate current research and open a novel therapeutic avenue. Credit: MPI f. Biochemistry An international team has discovered that the LRRK2 kinase regulates cellular trafficking by deactivating Rab proteins. This finding illuminates a novel route for therapeutic development and ... Read More »

Yale Researchers Identify Molecular Link between Obesity and Fatty Liver Disease

The high levels of obesity in the United States contribute to fatty liver disease, the most common form of liver disease. A newly published study from Yale University identifies molecular links between the two, and points to a possible therapy. Fatty liver disease — also known as nonalcoholic steatohepatitis or NASH — frequently progresses to cirrhosis and liver cancer. Currently ... Read More »

New Yale Study Links Childbearing to Accelerated Aging

New research from Yale University reveals the first evidence that childbearing may cause accelerated aging in women. The researchers tested 100 healthy postmenopausal women from five rural villages in southern Poland for biomarkers associated with accelerated aging. The study, conducted in partnership with researchers from Jagiellonian University Medical College in Krakow and the Polish Academy of Sciences, found that the ... Read More »

Yale Examines How Bacteria Might Trigger and Treat Autoimmune Disease

Kriegel has identified a promising gut bacterium that contains pieces similar to the body’s natural protein, which is then mistaken by the immune cells in APS. Photo credit: Carissa Violante New research from Yale University is exploring how beneficial bacteria that live in the gut might trick the body into an autoimmune reaction known as antiphospholipid syndrome. Doctors often describe ... Read More »

Yale Study Reveals Toxins in Fracking Fluids and Wastewater

New research from the Yale School of Public Health analyzed more than 1,000 chemicals in fluids used in and created by hydraulic fracturing (fracking), finding that many of the substances have been linked to reproductive and developmental health problems. Further exposure and epidemiological studies are urgently needed to evaluate potential threats to human health from chemicals found in fracking fluids ... Read More »

Immune Therapy Drug Prolongs Survival in Advanced Lung Cancer Patients

A newly published study involving patients with advanced non-small cell lung cancer resistant to chemotherapy has found a promising weapon in an immune therapy drug commonly used to treat other cancers. The findings were published December 19 in The Lancet and presented at the 2015 annual conference of the European Society for Medical Oncology in Singapore. The study, called KEYNOTE ... Read More »